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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT3
All Species:
17.27
Human Site:
S268
Identified Species:
38
UniProt:
O75175
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75175
NP_055331.1
753
81872
S268
P
T
S
T
T
S
S
S
P
I
P
P
S
P
A
Chimpanzee
Pan troglodytes
XP_512885
688
76993
D206
A
I
R
K
I
K
D
D
V
E
Y
Y
V
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541428
752
81536
S268
P
T
S
T
T
S
S
S
P
I
P
P
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0V4
751
81927
S268
P
T
S
T
T
S
S
S
P
I
P
P
S
P
A
Rat
Rattus norvegicus
NP_001100941
751
81862
S268
P
T
S
T
T
S
S
S
P
I
P
P
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086992
728
81088
S243
P
Q
T
G
V
A
A
S
P
P
G
Q
S
H
M
Zebra Danio
Brachydanio rerio
NP_956134
908
96903
I268
S
T
T
S
S
S
P
I
P
P
S
P
A
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610176
844
92349
P272
G
G
S
P
S
Q
S
P
V
T
V
Q
Q
I
L
Honey Bee
Apis mellifera
XP_395261
684
76726
I202
E
V
N
T
I
K
R
I
K
D
D
V
E
Y
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203995
878
98224
S268
S
S
S
L
P
S
T
S
N
H
S
K
D
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06102
836
94385
L269
S
L
Q
D
I
S
K
L
S
K
K
E
Q
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
N.A.
96.6
N.A.
95.2
95.4
N.A.
N.A.
N.A.
77.1
54.2
N.A.
41.5
51.9
N.A.
45.3
Protein Similarity:
100
88.1
N.A.
97.6
N.A.
96.4
96.6
N.A.
N.A.
N.A.
84
63.9
N.A.
57.7
65.7
N.A.
58.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
26.6
26.6
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
46.6
53.3
N.A.
20
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
0
0
0
0
10
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
10
0
0
10
10
0
10
10
0
10
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
10
0
0
28
0
0
19
0
37
0
0
0
19
0
% I
% Lys:
0
0
0
10
0
19
10
0
10
10
10
10
0
0
19
% K
% Leu:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
46
0
0
10
10
0
10
10
55
19
37
46
0
37
0
% P
% Gln:
0
10
10
0
0
10
0
0
0
0
0
19
19
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
28
10
55
10
19
64
46
55
10
0
19
0
46
0
10
% S
% Thr:
0
46
19
46
37
0
10
0
0
10
0
0
0
10
0
% T
% Val:
0
10
0
0
10
0
0
0
19
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _